St. Luke's is a full-service, not-for-profit hospital, located in Sioux City, Iowa. Our dedicated staff of doctors, nurses and other healthcare professionals strives to provide the most patient-centered care in Siouxland. With our areas of excellence in birthing, cardiology, radiology, pediatrics, surgery, rehabilitation and orthopedics, St. Luke's sets the standard for quality care. For the life of Siouxland.