St. Luke's is now UnityPoint Health | St. Luke's. A new name. A new day in health care. - Learn More -
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About Us

St. Luke's Health System provides an integrated delivery of care for patients in Sioux City, Iowa and the surrounding Siouxland area. Our patient and family -centered care ensures that patients receive a continuum of care that is seamless and positive. With a  commitment to quality, St. Luke's provides the best outcome for every patient every time!

With the support of  St. Luke's Health Foundation, St. Luke's offers full-service healthcare with clinics, a birth center, cancer care, heart and vascular services, GI, orthopedics, rehabilitation, surgery, emergency care and more. St. Luke's is also planning for the future of healthcare through its affiliation with St. Luke's College.

View our fast facts for a quick look at how many employees, patients and community organizations we impact every day.

Hospital History

St. Luke's traces its roots back to 1884 when Sioux City's first hospital, Samaritan Hospital, was opened. The hospital as it exists today was founded in 1966 through the consolidation of Lutheran and Methodist hospitals.

Over the years, St. Luke's has grown from a single, acute care hospital to a system encompassing St. Luke's Clinic Network. A member hospital of UnityPoint Health, St. Luke's is proud to provide high quality healthcare to thousands of patients in the tri-state service area.